Retrocyclin inhibits Gardnerella vaginalis biofilm formation and toxin activity
نویسندگان
چکیده
منابع مشابه
DNase inhibits Gardnerella vaginalis biofilms in vitro and in vivo.
Bacterial vaginosis is a highly prevalent and poorly understood polymicrobial disorder of the vaginal microbiota, with significant adverse sequelae. Gardnerella vaginalis predominates in bacterial vaginosis. Biofilms of G. vaginalis are present in human infections and are implicated in persistent disease, treatment failure, and transmission. Here we demonstrate that G. vaginalis biofilms contai...
متن کاملBiotypes of Gardnerella vaginalis.
A simple and reproducible scheme for identifying biotypes of Gardnerella vaginalis has been developed, based on reactions for lipase, hippurate hydrolysis, and beta-galactosidase. Among a total of 359 strains tested, eight biotypes were observed, the most common ones being types 1 (beta-galactosidase positive, lipase positive, hippurate positive), 2 (beta-galactosidase negative, lipase positive...
متن کاملAntimicrobial activity of vaginal lactobacilli against Gardnerella vaginalis and pathogens
Bacterial Vaginosis (BV) is a vaginal inflammatory disease, related to the high percentage of recurrences and serious obstetric, gynecological and reproductive problems. This is the reason why microbiologists and gynecologists search for new methods in the treatment and prevention of this condition. In this regard, the characterization of the biological activity of vaginal lactobacillus, that h...
متن کاملResistance of Gardnerella vaginalis to bactericidal activity of human serum.
To assess the sensitivity of Gardnerella vaginalis to the complement mediated bactericidal activity of serum, six laboratory strains were incubated with normal human serum and two strains freshly isolated from women with non-specific vaginitis (NSV) were each incubated with homologous patient serum. There was no significant difference between the number of organisms recovered from unheated or h...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2012
ISSN: 0305-7453,1460-2091
DOI: 10.1093/jac/dks305